This will allow a targeted understanding of where and when the brain adapts to and recovers from stroke. Zeiler’s team studies how brain reorganization evolves after stroke and interacts with training. Ultra-High Field MRI Study of Brain Reorganization after Stroke These projects are based on mechanisms known to measure and influence brain plasticity, and investigation of these areas holds promise for more complete recovery in stroke patients. Zeiler has created a multi-modal set of three research endeavors aimed at testing stroke outcomes during the time period of heightened recovery. elegans embryo, via cloning, characterization, and genetic mapping of a gene likely to be a P granule component. I studied P granules, organelles asymmetrically segregated during early development of the C. Undergraduate research, University of Colorado at Boulder 1995 to 1996 I also analyzed the 3’ untranslated regions of the glutamate receptor family. Using several different computer algorithms, I annotated genes on chromosomes 21 and 22 and subsequently validated gene godels using reverse transcriptase-polymerase chain reaction and sequencing techniques. Using genetic knockout mouse technology, I characterized the requirements for brain derived neurotrophic factor in the development and plastic changes of murine visual cortex. Thesis project research, University of Colorado at Boulder 1998 to 2002 Title: Brain Derived Neurotrophic Factor Signaling in Murine Visual Cortex.Ĭontinuing upon my thesis research, I further described part of the biochemical signaling pathway through which brain derived neurotrophic factor signals to influence visual cortical plasticity. Postdoctoral fellowship, University of Colorado at Boulder 2002 to 2003 Principal investigator, Johns Hopkins Department of Neurology 2010 to presentĪssessment of post-stroke neocortical plasticity using a multi-modal approach in the motor and visual cortices.

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